Nancy Guthrie latest: DNA from recovered glove undergoing lab testing
Nancy Guthrie latest: DNA from recovered glove undergoing lab testing

The search for 84-year-old Nancy Guthrie, the mother of “Today” show co-anchor Savannah Guthrie, entered its third week without an identified suspect as investigators grapple with limited forensic breakthroughs and widespread public interest.

Authorities confirmed Tuesday that DNA recovered from gloves found near Guthrie’s Tucson-area home had no match in the FBI’s national CODIS database, leaving detectives without a genetic lead to connect the unknown male in the case to any known offender records.

Read more: Who Is the Suspect in Nancy Guthrie’s Disappearance? Unofficial Sketch Emerges as Investigation Intensifies

Missing Since January 31

Guthrie was last seen at her Catalina Foothills home the night of Jan. 31, and her family reported her missing the next morning after she failed to show up for morning plans. Due to her age, medical needs and limited mobility, investigators have treated the case as a possible abduction from the start.

Investigators previously announced evidence consistent with a forced removal, including blood on the porch matching Guthrie’s DNA. A key piece of the investigation hinges on surveillance footage from her front-door camera showing a masked person outside the home in the hours before she was last seen.

FBI Suspect Description Still Central

The Federal Bureau of Investigation and Pima County Sheriff's Department continue to focus on the man caught in the recovered video. The suspect is described as:

  • Male

  • Roughly 5 feet 9 inches to 5 feet 10 inches tall

  • Average build

  • Wearing dark clothing, gloves and carrying a black 25-liter Ozark Trail “Hiker Pack” backpack

Investigators say the suspect appeared to tamper with or obscure the doorbell camera before walking away — a moment that has become the central visual clue in the hunt for answers.

DNA Results: No Match, But Investigation Continues

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The gloves, discovered about two miles from Guthrie’s residence, were submitted to both the FBI database and an out-of-state private laboratory. While multiple gloves collected during the search were determined to belong to searchers, at least one pair had DNA that did not match Guthrie, her family or any entries in CODIS.

Authorities say additional DNA evidence from the home is still being analyzed, and the investigation is not limiting itself to just the glove profile. “This process takes time,” a sheriff’s department official told local reporters, emphasizing that more testing and comparisons are ongoing.

Read more: Identify the Kidnapping Suspect: FBI Releases Description in Nancy Guthrie Case

Walmart Backpack Lead and Pacemaker Search

One unique element in the investigation has been the Ozark Trail backpack carried by the person in the video. Investigators are working with Walmart — the retailer where the backpack is sold — to try to trace potential purchasers who may have bought that specific 25-liter model around the relevant time frame.

In addition, authorities are attempting to locate Guthrie’s pacemaker, which reportedly disconnected from her phone in the early morning hours of Feb. 1. Law enforcement has collaborated with the pacemaker manufacturer and technology experts in hopes of using signal-detection equipment, including devices mounted on aircraft, to home in on a possible location.

Reward, Leads, and Public Appeals

The FBI has increased its reward to $100,000 for information leading to Guthrie’s discovery or the arrest and conviction of anyone involved in her disappearance. Investigators say they have received tens of thousands of tips, which are actively being reviewed.

A separate $100,000 reward has also been offered through local Crime Stoppers, aimed at encouraging anonymous information from the public.

Family Cleared of Suspicion

Sheriff Chris Nanos has publicly cleared Guthrie’s family members as suspects, saying they have been cooperative throughout the investigation and are themselves victims. The sheriff emphasized that unfounded speculation about family involvement harms the ongoing probe.

Ransom Communication and Ongoing Activity

Meanwhile, media outlets including TMZ have reported receiving purported ransom emails, which authorities have neither confirmed nor dismissed as authentic. Investigators continue to canvass businesses and review surveillance footage from the neighborhood, hoping someone will recognize the masked suspect or backpack seen in the video.

Sheriff: No Evidence Nancy Guthrie Was Taken to Mexico

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Sheriff Chris Nanos of the Pima County Sheriff's Department pushed back on speculation that Nancy Guthrie may have been transported across the U.S.–Mexico border, noting that investigators have found no indication she was taken out of the country.

In an interview with Fox News correspondent Jonathan Hunt, Nanos acknowledged that authorities are aware of southern Arizona’s proximity to Mexico and have considered that possibility. But he said there is currently no evidence to support a cross-border scenario.

“We check all the leads we have,” Nanos said. “We know where Mexico is in relationship to this, and it’s a possibility. But no, we have nothing to indicate that.”

Nanos added that federal partners, including the Federal Bureau of Investigation, routinely evaluate international angles in cases near the border. However, investigators have not uncovered credible information suggesting Guthrie was moved into Mexico.

Drone Captures Activity at Guthrie Home

As the search continues, aerial footage captured Tuesday by a Fox News drone showed two men walking the grounds of Guthrie’s property. The pair were seen moving around the residence, entering the backyard and later accessing the garage through an exterior-facing door.

Authorities have not confirmed the identities of the two men or whether they are directly connected to the investigation. Law enforcement officials have released few details about the latest operational steps, emphasizing that the case remains active and ongoing.

What Happens Next

As of Feb. 18 — Day 17 of the investigation — authorities have not identified a suspect, named a person of interest, or made an arrest. Detectives continue to process evidence, analyze DNA samples, track potential backpack purchasers, and explore signal detection from the pacemaker technology. Law enforcement officials emphasize the investigation is active and more operational activity can be expected in the coming days.

Officials urge anyone with credible information — especially related to the suspect description, the Ozark Trail backpack or unusual activity around Guthrie’s home on Jan. 31 or Feb. 1 — to contact the FBI tip line or local law enforcement.